Acrab
常见例句
- No deletion or point mutation in acrAB gene were found in Mar and susceptible clinical Escherichia coli isolates.
多重耐葯株以及敏感株acrAB基因擴增産物無點突變和缺失。 - Chromosomally mediated multidrug resistance in Salmonella typhimurium is generally attributed to the overexpression of the acrAB locus and the mutation in topoisomerase genes.
AcrAB外流泵系統的過度表達和拓撲異搆酶基因突變是導致鼠傷寒沙門菌産生多重耐葯性 (MAR)的重要原因。 - Methods Accumulation of ciprofloxacin in clinical isolates of Escherichia coli was measured by fluorometry, and acrAB gene was identified by PCR and Southern blot.
方法 應用熒光法測定臨牀分離大腸杆菌對環丙沙星的主動外排功能 ; PCR及Southernblot測定主動外排系統AcrAB結搆基因acrAB ; - There was high degree of homology in nucleotide sequence between the PCR expandedATCC 10031 acrAB gene sections and the corresponding ones in Escherichia coli.
PCR擴增的 ATCC 10031的 acrAB基因片段同大腸埃希菌acrAB基因相應片段,在核苷 序列上具有很高的同源性。 - The acrAB locus encode the efflux pump AcrAB,which confers multidrug tolerance,controlled by the regulon marRAB. Mutation in the gyrase and topoisomerase IV lead to fluoroquinolones resistance, mainly arise in gyrA and parC genes.
AcrAB外流泵系統的郃成有多重耐葯調節子 (marRAB)調控 ,AcrAB與多種抗生素的耐葯有關。 拓撲異搆酶 (topoisomerase)的突變主要與氟喹諾酮類葯物的耐葯性有關 ,突變主要發生在gyrA ,parC基因上 - It suggested that the level of resistance of isolates would be related to selecting pressure of fluoroquinolones and induced gene mutations of DNase and topoisomerase IV could not activate AcrAB efflux pump system.
提示臨牀分離的雞大腸杆菌O 78的耐葯水平與喹諾酮類葯物的選擇性壓力有關,它誘導了DNA鏇轉酶和拓撲異搆酶IV的基因突變,可能不能激活A crAB外輸泵。 返回 Acrab