rivastigmine

基本解释

Rivastigmine, a sort of acetylcholinesterase inhibitor, is used in the symptomatic treatment of mild to moderate Alzheimer's Disease (AD).
酒石酸卡巴拉汀是一种乙酰胆碱酯酶抑制剂,用于治疗中、轻度老年痴呆症(即阿尔茨海默氏症:AD),目前已在瑞士上市,市场前景看好。
In this essa y, we have studied a synthesis routine of Rivastigmine, which is suitable of dom estic production.We prepared the racemic and gained (S)-isomer by the resoluti on with D-DTTA.
该文研究了一条适合国内生产的合成路线，先合成外消旋体，再和D-酒石酸衍生物形成非对映体盐，通过分级结晶进行分离，获得S-异构体。
Keywords rivastigmine hydrogen tartrate;acetylcholine esterase（AchE） inhibitor;Alzheimer s disease;synthesis;
重酒石酸利斯的明;乙酰胆碱酯酶抑制剂;阿尔茨海默病;合成;
Keywords chromatography;high pressure liquid;rivastigmine;cholinesterase-inhibitors;dissolution;
色谱法;高压液相;利斯的明;胆碱脂酶抑制剂;溶出度;
Keywords High performance liquid chromatography;enantioseparation;vancomycin;chiral stationary phase;rivastigmine;
高效液相色谱法;对映体拆分;手性固定相;卡巴拉汀;