Septin
常见例句
- Septin 1 is Aurora-B’s substrate in vivo, they two both take part in the regulation of cytokinesis.
Septin1是Aik2的细胞内底物,二者共同参与调控胞质分裂。 - Aurora-B can phosphorylate Septin 1.Ser-307 and Ser-315 is its important sites of phosphorylation.
Aik2可磷酸化 Septin1,Ser-307、315是重要的磷酸化位点。 - In vivo Location demonstrated that Septin 1 is located in centriole before mitosis, and later slowly moved to the milieu of nucleus.
细胞内定位显示:Septin1 在有丝分裂前定位于中心粒,后慢慢迁移至核周围。 - Recently, more and more data suggest that some septin family members participate in the pathogenesis of different diseases including neoplasia, neurodegeneration and infections.
更引起研究人员重视的是: 最近有大量数据表明, 这一家族的一些成员与肿瘤发生、神经功能障碍和病原微生物感染的过程直接相关。 - After Septin 1 is phosphorylated, it can enhance the kinase’s activity by feedback effect, however we found on such feedback effect in mutant of Septin 1.
Septin1被磷酸化后可反馈性地增强激酶活性,而突变体则没有这种反馈性的效应。 - Keywords Aurora-B;Septin 1;phosphorylation;mutation;cytokinesis;polyploid;
磷酸化;突变;胞质分裂;多倍体; 返回 Septin